RAF Typhoon FGR4s have operated alongside France's air force in a combined operation against an hidden munitions depot in Syrian territory used by the Daesh militant organization, according to the UK's MoD.
The site, pinpointed through reconnaissance, was assessed as storing arms and explosives, the release indicated, and was situated in mountains just to the north of the historic site of Palmyra in Syria's central region.
"Our fighter planes utilized precision-guided Paveway IV munitions to strike a series of approach shafts leading to the site... preliminary assessments indicate the objective was successfully hit," the MoD said.
There was no sign of any harm to civilians in the operation conducted Saturday night and every plane involved returned safely, the ministry further stated.
The Typhoon fighters were supported by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as ISIS - enforced extremist governance over significant areas in Iraq and Syria until 2019.
"This strike shows our UK leadership, and commitment to stand shoulder to shoulder with our allies, to stamp out any re-emergence of Daesh and their violent and radical beliefs in the Middle East," Britain's Defence Chief the Defence Secretary stated.
UK warplanes have performed overwatch operations over Syria to "forestall any attempted resurgence" of Islamic State following its defeat at the battle of Baghuz in 2019, the authorities noted.
"I want to thank the personnel of the UK armed forces participating in this operation for their skill and their courage," the Defence Secretary commented. "They were among a great many British troops deployed over the festive period. This operation, to eliminate dangerous terrorists who endanger our safety, highlights how British military are prepared to act, throughout the year, protecting the UK within its borders and strong abroad."
Last December, the US military executed what it described as a "major assault" targeting Islamic State objectives in the country, after an assault killed two US servicemembers and a civilian interpreter in Palmyra.
The UN says IS still maintains roughly 5-7 thousand fighters in both countries.